Reserpine USP/BP
General Information
Reserpine is a naturally extracted alkaloid from root of Rauwolfia vomitoria, Rauwolfia Serpentina and these plants mainly grown in Africa and India. Contents of Reserpine in rauwolfia vomitoria more than Rauwolfia serpentina. It is used for treatment of hypertension with combination of other medicines. This drug is largely used in European and American countries for treatment of High blood pressure.
Chemical Name: (3beta, 16beta, 17alpha, 18beta, 20alpha) - 11, 17 - dimethoxy-18 - [(3, 4, 5-trimethoxybenzoyl) oxy] yohimban-16-carboxylic acid methyl ester; Methylreserpate 3,4,5-trimethoxybenzoic
Product Description & identification
| Details |
| CAS NO. |
50-55-5 |
| EINECS NO. |
200-047-9 |
| FORMULA |
C33H40N2O9 |
| MOLECULAR WEIGHT |
608.69 |
| SYNONYMS |
RESERPOID, SERPALOID |
| PACKING |
500 Gms,1, 5Kg |
| MELTING POINT |
109°C to 112°C |
Product Specification
| Parameters |
Requirement / Limit |
Results |
| Identification |
White to slightly yellow color powder |
off white powder |
| Identification by U.V. |
Should comply |
Complies |
| Loss on drying |
0.5 % Max |
0.36 % |
Sulphated Ash |
NMT 0.1 % |
0.07 % |
S.O.R. on dried basis |
(-) 116o to (-) 128o |
(-) 122.4o |
| Solubility in water |
Practically insoluble |
Practically insoluble |
Solubility in ether |
Practically insoluble |
Practically insoluble |
| Solubility in ethanol(96%) |
Very slightly soluble |
Very slightly soluble |
| Solubility in chloroform |
Freely Soluble |
Freely soluble |
| Total Alkaloid on dried basis |
98.0 % to 102.0 % |
99.62 % |
| Assay by HPLC |
97.0 % to 101 % |
99.32 % |
This product confirm to specifications.
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